York Pei Selected Research

TOR Serine-Threonine Kinases

1/2022	Shared pathobiology identifies AMPK as a therapeutic target for obesity and autosomal dominant polycystic kidney disease.
1/2020	Targeting AMP-activated protein kinase (AMPK) for treatment of autosomal dominant polycystic kidney disease.

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York Pei Research Topics

Disease

37	Autosomal Dominant Polycystic Kidney (ADPKD) 12/2023 - 06/2003
15	Cysts 01/2023 - 10/2008
8	Disease Progression 12/2023 - 01/2017
6	Polycystic Kidney Diseases (Polycystic Kidney Disease) 11/2023 - 02/2004
6	Chronic Renal Insufficiency 09/2021 - 07/2006
4	Chronic Kidney Failure (Chronic Renal Failure) 01/2023 - 05/2003
4	Fibrosis (Cirrhosis) 01/2023 - 07/2010
3	Neoplasms (Cancer) 01/2023 - 07/2011
3	Hypertension (High Blood Pressure) 07/2010 - 06/2002
2	Inflammation (Inflammations) 11/2023 - 01/2023
2	IGA Glomerulonephritis (IGA Nephropathy) 01/2023 - 10/2011
2	Kidney Diseases (Kidney Disease) 01/2023 - 01/2016
2	Pain (Aches) 01/2021 - 01/2020
2	Proteinuria 01/2020 - 05/2015
2	Cystic Kidney Diseases (Cystic Kidney Disease) 09/2019 - 01/2019
2	Polycystic liver disease 10/2018 - 01/2015
2	Hereditary Nephritis (Alport Syndrome) 01/2018 - 01/2017
2	Tuberous Sclerosis (Bourneville's Disease) 03/2016 - 01/2016
2	Hypoxia (Hypoxemia) 07/2009 - 06/2002
1	Epidermal Cyst (Sebaceous Cyst) 01/2023
1	Body Weight (Weight, Body) 01/2023
1	Polyuria 01/2023
1	Obesity 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Overweight 01/2022
1	Ureteral Obstruction 09/2021
1	Intracranial Aneurysm (Cerebral Aneurysm) 01/2021
1	Renal Insufficiency (Renal Failure) 01/2020
1	Constipation 01/2020
1	Shock 01/2020
1	Infections 01/2020
1	Diarrhea 01/2020
1	Segmental glomerulosclerosis 01/2018
1	Nephrosis 03/2017
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 03/2017
1	Ichthyosis (Xeroderma) 03/2017
1	Angiomyolipoma 03/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2016

Drug/Important Bio-Agent (IBA)

9	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 06/2003
7	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2004
4	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2017
4	CreatinineIBA 01/2017 - 05/2003
3	salicylsalicylic acid (salsalate)IBA 11/2023 - 09/2019
3	Peptides (Polypeptides)IBA 01/2023 - 01/2016
3	AMP-Activated Protein KinasesIBA 01/2022 - 09/2019
3	TRPP Cation ChannelsIBA 01/2022 - 02/2004
3	Collagen Type IV (Type IV Collagen)IBA 03/2021 - 05/2015
3	Angiotensin IIIBA 01/2017 - 06/2002
2	Tolvaptan FDA Link 12/2023 - 01/2023
2	RNA (Ribonucleic Acid)IBA 11/2023 - 01/2020
2	Adenosine Monophosphate (AMP)IBA 11/2023 - 11/2017
2	Urea (Carbamide)FDA LinkGeneric 01/2023 - 09/2019
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2023 - 09/2021
2	TOR Serine-Threonine KinasesIBA 01/2022 - 01/2020
2	Messenger RNA (mRNA)IBA 09/2021 - 01/2017
2	Angiotensin-Converting Enzyme 2IBA 01/2017 - 06/2002
2	trans-sodium crocetinate (crocetin)IBA 03/2016 - 01/2016
2	Transcription Factors (Transcription Factor)IBA 07/2009 - 04/2005
1	Protein Kinases (Protein Kinase)IBA 11/2023
1	Antidiuretic Hormone Receptor AntagonistsIBA 01/2023
1	Epidermal Growth Factor (EGF)IBA 01/2023
1	AntioxidantsIBA 01/2023
1	Immunoglobulin A (IgA)IBA 01/2023
1	Sodium Tetradecyl Sulfate (Sotradecol)FDA Link 01/2022
1	Recombinant ProteinsIBA 01/2021
1	Vorinostat FDA Link 01/2020
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	2,5- dibromo- 2- (beta- naphthyl)indan- 1,3- dioneIBA 01/2020
1	NitrogenIBA 09/2019
1	CanagliflozinIBA 09/2019
1	Metformin (Glucophage)FDA LinkGeneric 09/2019
1	tetrachloroisophthalonitrile (Bravo)IBA 10/2018
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2018
1	Cysteine (L-Cysteine)FDA Link 01/2018
1	GuanineIBA 01/2018
1	NucleotidesIBA 01/2018
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2018
1	Amino Acids FDA Link 01/2018
1	ThymineIBA 01/2018
1	bcr-abl Fusion ProteinsIBA 11/2017
1	bosutinibIBA 11/2017
1	sphingosine 1-phosphate lyase (aldolase)IBA 03/2017
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 03/2017
1	LyasesIBA 03/2017
1	angiotensin I (1-7)IBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017
1	AngiotensinsIBA 01/2017
1	Extracellular Matrix ProteinsIBA 01/2017

Therapy/Procedure

8	Therapeutics 12/2023 - 10/2003
3	Sclerotherapy 01/2023 - 11/2019
3	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2021 - 07/2015
2	Precision Medicine 01/2021 - 01/2019
1	Conservative Treatment 09/2023
1	Caloric Restriction 01/2022
1	Ketogenic Diet 01/2022
1	Pain Management 01/2021
1	Lithotripsy (Extracorporeal Shockwave Lithotripsy) 01/2020
1	Percutaneous Nephrolithotomy 01/2020